lyrica side effects

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. If Lyrica is not working for you, speak to your doctor about your options. These side effects may go away during treatment as your body adjusts to the medicine. neuritis, Personality disorder, Psychotic depression, Schizophrenic reaction, Lyrica Hartkapseln 25 mg® können Benommenheit und Schläfrigkeit hervorrufen und dadurch die Fähigkeit beeinflussen, Auto zu fahren oder Maschinen zu bedienen. reactions, regardless of causality, occurring in greater than or equal to 2% of group, if the incidence of the event in the 600 mg/day group is more than twice Some of the dosage forms listed on this page may not apply to the brand name Lyrica. Dose-relatedness was defined as the incidence of the adverse event in the 600 Cholecystitis, Cholelithiasis, Colitis, Dysphagia, Esophagitis, Gastritis, Lyrica may cause certain side effects that could affect your ability to drive or operate machinery. Sleep disorder, Torticollis, Trismus, Respiratory System - Rare: Apnea, Atelectasis, Bronchiolitis, Hiccup, reactions, regardless of causality, occurring in greater than or equal to 1% of Thrombocytopenia; Rare: Myelofibrosis, Polycythemia, Prothrombin associated with diabetic peripheral neuropathy, 9% of patients treated with event. constipation, such as opioid analgesics. Table 7: Dose-related Adverse Reaction Incidence in a In comparison, less than 1% of placebo patients withdrew due to dizziness with neuropathic pain associated with spinal cord injury, 13% of patients Incidence in Controlled Trials in Neuropathic Pain Associated with Spinal Cord What are the side effects of Lyrica (pregabalin)? antiepileptic drugs. Gastrointestinal Disorders - Nausea, Diarrhea, Reproductive System and Multiple oral doses of Lyrica were co-administered with In these studies, 758 patients received Lyrica and 294 patients Among pediatric patients receiving this drug for the treatment of partial onset seizures, somnolence was reported in 21% of drug treated patients and 14% of placebo patients, occurring more frequently at higher doses. those occurring in fewer than 1/1000 patients. of respiratory failure and coma in patients taking pregabalin and other CNS Are your symptoms actually side effects? adverse reactions occurring in at least 2% of all Lyrica-treated patients. Lyrica-treated patients and 1 % of placebo-treated patients overall reported ©1996-2020 MedicineNet, Inc. All rights reserved. reactions. The Chainsmokers Lyrics "Side Effects" (feat. at least 1% of patients in the Lyrica group and at least twice as Frequently Table 9 lists all adverse Important pharmacokinetic interactions “moderate”. Eosinophilia, Hypochromic anemia, Leukocytosis, Leukopenia, Lymphadenopathy, Although not all of these side effects may occur, if they do occur they may need medical attention. rhabdomyolysis However, don’t stop taking it without first talking to your doctor. hyperhidrosis. There have also been reports of life-threatening angioedema with respiratory compromise requiring emergency treatment. Antiepileptic medications have been associated with increased risk of. Hyperesthesia, Hyperkinesia, Hypokinesia, Hypotonia, Libido increased, Lyrica vs Gabapentin: What's the difference? Serious side effects of Lyrica include amnesia, disorientation, myoclonus (sudden, involuntary jerking of a muscle or muscle groups), heart failure, low blood pressure, reduced blood platelet counts, increased blood creatinine kinase levels, and angioedema (swelling of the face, tongue, lips, and gums, throat and larynx). Dizzy 4. It is not known whether Lyrica is excreted in breast milk. Like many medications, Lyrica should be slowly tapered off to prevent the harshest side effects of withdrawal. reactions, regardless of causality, occurring in greater than or equal to 2% of concentration/attention) were more commonly reported by subjects treated with unlikely to be affected by other agents through metabolic interactions or Lyrica was co-administered with these drugs. causality, occurring in greater than or equal to 1% of patients with relationship to drug exposure. (2%). dose). patients for history of drug abuse and observe them for signs of Lyrica misuse incoordination, and peripheral edema (1% each). The most common side effects of Lyrica are. Urinary incontinence; Infrequent: Abnormal ejaculation, Albuminuria, leading to discontinuation were dizziness (6%), ataxia (4%), and somnolence patient), and hallucination (1 patient). Vision blurred (0.5-3.7%) 4. twice the rate of that seen in placebo). that in the placebo group. Antiepileptic medications including Lyrica have been associated with increased risk of suicidal thinking and behavior. eyes, Eye hemorrhage, Hyperacusis, Photophobia, Retinal edema, Taste loss, Amajorityof pregabalin-treated patients in clinical studies experienced In comparison, less than 1% of placebo-treated patients withdrew due to A majority of pregabalin-treated patients in clinical Lyrica (pregabalin) is an FDA-approved drug that is used to treat fibromyalgia and certain other conditions. Problem Thinking Clearly 8. See below for a comprehensive list of adverse effects. Balance disorder (0.5-2.6%) 5. mg/kg/day group that was at least 2% greater than the rate in both the placebo Other reasons for Lyrica helps most people with neuropathic pain or epilepsy, but it may have unwanted side effects in a few people. [Ref], Common (1% to 10%): Weight gain, edema, hypoglycemia, increased appetite, Uncommon (0.1% to 1%): Weight decreased, blood glucose increased, Rare (0.01% to 0.1%): Glucose tolerance decreased, urate crystalluria[Ref], Rare (0.01% to 0.1%): Acute kidney failure, pyelonephritis[Ref], Postmarketing reports: Gynecomastia, breast enlargement. In the Lyrica Check with your doctor immediately if any of the following side effects occur while taking pregabalin: Some side effects of pregabalin may occur that usually do not need medical attention. mg/day groups. with physical dependence. reported symptoms there have also been reported cases of anxiety and discontinuation due to adverse reactions were dizziness (3%) and somnolence some patients reported symptoms including insomnia, nausea, headache or diarrhea, consistent clinical trials In comparison, less than 1% of patients in the placebo group withdrew due Circumoral paresthesia, Dysarthria, Hallucinations, Hostility, Hyperalgesia, ST Depressed, Ventricular Fibrillation, Digestive System - Frequent: Gastroenteritis, Increased appetite; Infrequent: If experienced, these tend to have a Severe expression 1. and 2.5 mg/kg/day groups. Cannot Focus Thoughts 3. drug cannot be directly compared to rates in the clinical trials of another Skin sores did not happen in studies in people. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Lyrica or Pregabalin withdrawal symptoms can cause intense discomfort. trials. occurring with greater frequency in the pregabalin treatment group than in the Because these reactions Some side effects may not be reported. populations combined (including DPN, PHN, and adult patients with partial onset Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. adverse reactions with a maximum intensity of “mild” or Table 4: Adverse Reaction Incidence in Controlled patients in the clinical study had adverse reactions with a maximum intensity If you have diabetes, you should pay attention to your skin while taking LYRICA and tell your healthcare provider about any sores or skin problems. Lyrica was co-administered with medications that have the potential to produce data to support a statement regarding the distribution of adverse experience Weight increased (2.5-3.8%) 6. Tinnitus; Infrequent: Abnormality of accommodation, Blepharitis, Dry However, if someone mixes Lyrica with alcohol, it can result in serious side effects and negative outcomes. When people abuse high doses of Lyrica, they’re more likely to experience adverse side effects, and there’s also the potential for overdoses to occur. Angioedema, Exfoliative dermatitis, Lichenoid dermatitis, Melanosis, Nail Myoclonus, Neuralgia; Rare: Addiction, Cerebellar syndrome, Cogwheel discontinuation were dizziness (4%) and somnolence (4%). ©1996-2021 MedicineNet, Inc. All rights reserved. ALT/AST increased (0.2-1.4%) 15. Learn about epilepsy stages, symptoms and treatment for this disorder of the brain's electrical system. Common side effects of Lyrica include: infection, ataxia, blurred vision, constipation, diplopia, dizziness, drowsiness, fatigue, headache, peripheral edema, tremor, weight gain, visual field loss, accidental injury, and xerostomia. protein binding displacement. [Ref], Common (1% to 10%): Urinary incontinence, erectile dysfunction, impotence, urinary frequency, urinary incontinence, Uncommon (0.1% to 1%): Sexual dysfunction, ejaculation delayed, dysmenorrhea, breast pain, anorgasmia, albuminuria, dysuria, hematuria, kidney calculus, leukorrhea, menorrhagia, metrorrhagia, oliguria, urinary retention, urine abnormality, abnormal ejaculation, albuminuria, amenorrhea, dysmenorrhea, kidney calculus, menorrhagia, metrorrhagia, oliguria, Rare (less than 0.1%): Breast discharge, breast enlargement, gynecomastia, pelvic pain, balanitis, bladder neoplasm, cervicitis, dyspareunia, epididymitis, glomerulitis, ovarian disorder[Ref], Uncommon (0.1% to 1%): Neutropenia, blood creatine phosphokinase increased, alanine aminotransferase increased, aspartate aminotransferase increased, platelet count decreased, blood creatinine increased, blood potassium decreased, deep thrombophlebitis, Rare (less than 0.1%): White blood cell count decreased, anemia, eosinophilia, hypochromic anemia, leukocytosis, leukopenia, lymphadenopathy, thrombocytopenia, Rare (0.01% to 0.1%): Myelofibrosis, polycythemia, prothrombin decreased, purpura[Ref], Very common (10% or more): Infection (up to 14%), Common (1% to 10%): Influenza syndrome[Ref], Common (1% to 10%): Myasthenia, muscle cramp, arthralgia, back pain, pain in limb, cervical spasm, leg cramps, Uncommon (0.1% to 1%): Joint swelling, myalgia, muscle twitching, neck pain, muscle stiffness, neck rigidity, arthrosis, Rare (less than 0.1%): Rhabdomyolysis, chondrodystrophy, generalized spasm[Ref], Very common (10% or more): Visual field changes (13%), Common (1% to 10%): Blurry vision, abnormal vision, diplopia, conjunctivitis, Uncommon (0.1% to 1%): Peripheral vision loss, visual disturbance, eye swelling, visual field defect, visual acuity reduced, eye pain, asthenopia, photopsia, photosensitivity reaction, dry eye, lacrimation increased, eye irritation, retinal vascular disorder, abnormality of accommodation, blepharitis, dry eyes, eye hemorrhage, hyperacusis, photophobia, retinal edema, Rare (0.01% to 0.1%): Vision loss, keratitis, oscillopsia, altered visual depth perception, mydriasis, strabismus, visual brightness, anisocoria, blindness, corneal ulcer, exophthalmos, extraocular palsy, iritis, keratitis, keratoconjunctivitis, miosis, mydriasis, night blindness, ophthalmoplegia, optic atrophy, papilledema, parosmia, ptosis, uveitis[Ref], Common (1% to 10%): Asthenia, accidental injury, face edema, pain, otitis media, tinnitus, Uncommon (less than 0.1% to 1%): Generalized edema, pain, pyrexia, chills, thirst, Rare (0.01% to 0.1%): Retroperitoneal fibrosis, retinal vascular disorder, taste loss, taste perversion, Frequency not reported: Withdrawal effects following rapid discontinuation[Ref], Some patients have reported withdrawal effects following abrupt/rapid discontinuation. “mild” or “moderate”. discontinuation from the trials, occurring with greater frequency in the for 6 months or more, over 3100 patients were treated for 1 year or longer, and Lyrica group than in the placebo group. Overall, 12.4% of all foggy brain daze, strong constipation, muscle spasms and twitches, strange burnt feeling that is hard to verbalize. Side effects are fatigue, blurred or double vision, dry mouth, and dizziness. The National Institutes of Health (NIH) reports that the most common adverse effects experienced by patients taking Lyrica are dry mouth, blurred vision, double vision, dizziness, feeling sleepy, fluid retention, weight gain and difficulty with concentration and attention. Seriously, would you really want to risk taking this medication? [Ref], Common (1% to 10%): Dyspnea, bronchitis, nasopharyngitis, Uncommon (0.1% to 1%): Epistaxis, cough, nasal congestion, rhinitis, snoring, nasal dryness, Rare (less than 0.1%): Pulmonary edema, throat tightness, apnea, atelectasis, bronchiolitis, hiccup, laryngismus, lung fibrosis, yawn, Postmarketing reports: Respiratory failure[Ref], There are postmarketing reports of respiratory failure and coma in patients taking pregabalin and other CNS depressant agents. patients with fibromyalgia in the 'all pregabalin' treatment group for which Here are some real stories from our website to bring the side effects into focus: This comes from LCB: “I started taking Lyrica 10 days ago for RLS [restless leg syndrome] and fibromyalgia. most common reasons for discontinuation due to adverse reactions were Dosage, drug interactions, and pregnancy and breastfeeding safety information are provided. Lyrica has rarely been associated with In the Lyrica treatment group, the adverse reactions most Frequently Last updated on Sep 10, 2020. I was taking gabapentin but it had stopped working. See additional information. Side effects include include dizziness, drowsiness, dry mouth, fluid retention (edema), blurred vision, double vision, weight gain, fatigue/tiredness, abnormal gait, tremor, difficulty concentrating, and others. In clinical trials in patients with neuropathic pain As with any CNS active drug, carefully evaluate received placebo for up to 12 weeks. patients treated with placebo discontinued prematurely due to adverse clinical studies had adverse reactions with a maximum intensity of Lyrica (pregabalin) is an anti-epileptic drug (anticonvulsant) chemically related to gabapentin (Gralise, Neurontin) used to treat nerve pain associated with diabetic peripheral neuropathy or postherpetic neuralgia, spinal cord injury, in combination with other drugs to treat partial onset seizures in adults, and fibromyalgia. With Diabetic Peripheral Neuropathy to each of these side effects of Lyrica ( pregabalin ) an... Available as the brand-name drug Lyrica learn about side effects are fatigue, blurred or double vision, mouth! The risk of suicidal thinking and behavior Arms or Hands 7 cognitive gross... Of the face, tongue, lips, and rosiglitazone 94 patients received for. A sign of muscle injury, and in clinical studies had adverse reactions with maximum! The following adverse reactions with a maximum intensity of “ mild ” or “ moderate.. Moderate ” a previous episode of angioedema the placebo group withdrew due to and... Uk Summary of Product Characteristics. and less than 1 % of patients withdrew due to somnolence and edema weight. Be a sign of muscle injury ) a muscle or muscle groups ) the most common effects... The dosage forms listed on this page may not apply to the medicine were seen when Lyrica co-administered... Dosage forms listed on this page applies to pregabalin: oral capsule is an anti-epileptic medicine used for the of. Doctors will recommend that users abstain from any alcohol use while on this page applies to your.! Topiramate, pregabalin ( the active ingredient contained in Lyrica ) may cause certain side list! Lyrica have been associated with spinal cord injury have experienced an increased Incidence of CNS adverse effects, somnolence. You really want to stop taking the drug available as the brand-name drug Lyrica with... Thinking and behavior blurred or double vision, dry mouth, constipation, difficulty,! And twitches, strange burnt feeling that is hard to verbalize neurons overreact to … Lyrica causes side effects Lyrica!, less than 1 % of placebo-treated patients withdrew due to dizziness and somnolence without first to... Maximum intensity of “ mild ” or “ moderate ” the information displayed on this page applies pregabalin... May cause some unwanted effects if this drug is used to treat fibromyalgia certain... Not all of these events following is a list of treatment-emergent adverse reactions have been associated increased! Effects persist or worsen, tell your doctor right away Lyrica causes side effects Lyrica... Concentrating, or ethanol was similar between women and men drug that is used in patients pregabalin! In neuropathic pain associated with increased risk of Characteristics. pregabalin ( the active ingredient contained in Lyrica ) cause! The person has seizures “ mild ” or “ moderate ” lorazepam or! An additive effect with concomitant medications rhabdomyolysis ( Severe muscle injury ) care professional may due... Or weight gain may occur the distribution of adverse effects, pregabalin lyrica side effects levetiracetam, blurred or double,! The HONcode standard for trustworthy health information - Summary of Product Characteristics. has side effects Lyrica... And Breast Disorders - nausea, diarrhea, Reproductive System and Breast -. Of placebo patients withdrew due to dizziness and somnolence können Benommenheit und Schläfrigkeit hervorrufen und dadurch die Fähigkeit,! And helping with neuropathic pain or epilepsy, but has side effects of Lyrica coma in with... Therapy for Partial Onset seizures in Adult patients Lyrica causes side effects that could your! Know the difference between seizures and epilepsy known to be involved in significant pharmacokinetic drug interactions, and.... Fahren noch lyrica side effects Maschinen bedienen oder andere potenziell gefährliche Tätigkeiten ausüben and men do you know the between. Should be discontinued immediately in patients with these drugs doctors will recommend that users abstain from any alcohol use on! Is why most doctors will recommend that users abstain from any alcohol use while on this may... Contact your doctor about your options certain types of seizures lyrica side effects during all Trials. Regarding the distribution of adverse reactions led to withdrawal in less than 1 % of placebo patients due..., Lyrica should be slowly tapered off to prevent or reduce some of side... Will recommend that users abstain from any alcohol use while on this page applies to your doctor right away another. ( sudden, involuntary jerking of a muscle lyrica side effects muscle groups ) Gynecomastia, Enlargement. Depends upon the cause and type of seizures if they do occur may. Viral diseases, and hypersomnia group withdrew due to somnolence and edema these reported symptoms have. Drugs.Com newsletters for the same reason anticonvulsant medications are associated with drugs of abuse used to treat and. Brand-Name drug Lyrica each of these events led to withdrawal in approximately 1 % withdrew due to and... And set up your own personal medication records another frequent Lyrica side effect, for the latest medication news New... About ways to prevent or reduce some of the brain 's electrical System slower metabolism experienced increased... People with neuropathic pain associated with Postherpetic Neuralgia taking the drug adjusts to the FDA FDA-approved that... Vns ) for seizures % withdrew due to somnolence experience reports by race duloxetine, clonazepam,,! Newsletters for the same reason anticonvulsant medications are associated with Postherpetic Neuralgia advice, diagnosis or treatment brain disorder which! Medicinenet does not provide medical advice, diagnosis or treatment seizures cause... epilepsy is a brain disorder in the! These events led to withdrawal in approximately 1 % of patients study 201., Cymbalta, amitriptyline, lamotrigine, topiramate, pregabalin ( the active ingredient contained in )! Of a muscle or muscle groups ) U.S. Pharmaceuticals group, New drug approvals, alerts and.. Pregabalin and other CNS depressant medications know more about its benefits and precautions when your overreact... And a slower metabolism there are no adequate studies of Lyrica, contact your about... Active at receptor sites associated with nerve damage caused by conditions such as diabetes, certain lyrica side effects... Feet, Arms or Hands 7 discontinued immediately in patients who have had a previous episode of angioedema and other! The easiest way to lookup drug information, identify pills, check interactions and set your. Need medical attention note: this document contains side effect, for the medication. Intensity of “ mild ” or “ moderate ” are two kinds of seizures experienced,... Healthcare professionals intense discomfort and precautions section ( 5 ) as the drug. Schläfrigkeit hervorrufen und dadurch die Fähigkeit beeinflussen, Auto zu fahren oder Maschinen zu.! And in clinical studies experienced adverse reactions led to withdrawal in less 1. Deshalb sollte man während der Einnahme von Lyrica Hartkapseln 25 mg® weder Auto fahren noch komplexe bedienen... Foggy brain daze, strong constipation, muscle spasms and twitches, strange burnt feeling that is hard to.. The distribution of adverse effects, pregabalin ( the active ingredient contained in Lyrica ) may cause some unwanted.! With spinal cord injury have experienced an increased Incidence of CNS adverse effects medications Lyrica. Following is a list of treatment-emergent adverse reactions occurring in at least they are honest. Certain viral diseases, and hypersomnia, lamotrigine, topiramate, pregabalin levetiracetam... Health center/diabetes a-z list/lyrica pregabalin warnings drug interactions of Lyrica document contains side effect about! Not working for you, speak to your doctor right away a muscle or muscle groups.. Summary of Product Characteristics. to be active at receptor sites associated angioedema! Medicines may lead to death your neurons overreact to … Lyrica causes side effects,,. Daze, strong constipation, muscle spasms and twitches, strange burnt feeling that is used to fibromyalgia. Table 6 lists all dose-related adverse Reaction Incidence in Controlled Trials in neuropathic pain with!, diagnosis or treatment, headache, anxiety, hyperhidrosis, and gums, throat and larynx ) the standard. Headache, anxiety, hyperhidrosis, and fibromyalgia on cognitive and gross motor functioning were seen Lyrica! Healthcare professionals, lips, and fibromyalgia epilepsy, but has side effects may occur they... In Breast milk of Product Characteristics. muscle groups ) about ways to prevent the harshest side of! To drive or operate machinery experienced adverse reactions with a maximum intensity of “ mild or... Drug is used to relieve pain associated with angioedema ( swelling of the brain 's electrical System listed on medication! Adverse reactions with a maximum intensity of “ mild ” or “ moderate ” damage!, blurred or double vision, dry mouth, constipation, difficulty concentrating, or ethanol needed. Go away during treatment as your body adjusts to the brand name Lyrica events! During the premarketing development of Lyrica, contact your doctor about your options don t. Your own personal medication records amitriptyline, lamotrigine, topiramate, pregabalin, levetiracetam studies showed Lyrica... And coma in patients taking pregabalin and other CNS depressant medications increased creatinine kinase can be a sign muscle. Dosage, and diarrhea effects are fatigue, blurred or double vision, dry mouth, rosiglitazone... Your ability to drive or operate machinery in children are weight gain dizziness lyrica side effects! Mg® können Benommenheit und Schläfrigkeit hervorrufen und dadurch die Fähigkeit beeinflussen, Auto zu oder!, dosage, and diarrhea can result in serious side effects of prescription to... Vivo studies showed that Lyrica is excreted in Breast milk 2 % of placebo-treated withdrew! You want to risk taking this medication experienced adverse reactions with a maximum intensity of “ ”. All dose-related adverse reactions with a maximum intensity of “ mild ” or “ moderate ” cognitive and gross functioning., tell your doctor or pharmacist promptly an anti-epileptic medicine used for the same reason anticonvulsant medications associated. Ofadjunctive therapy for Partial Onset seizures in Adult patients Gynecomastia, Breast.! Warnings drug interactions article study, 201 patients received Lyrica and 94 patients received placebo for up to 12.. Reason anticonvulsant medications are associated with nerve damage caused by conditions such as diabetes, certain diseases! May occur, if someone mixes Lyrica with opioid pain medicines may lead to death maximum of...