Therefore, laboratory animal handling, care and its management is an integral part of any research laboratories, especially laboratories of animal research institutes. 18.1): Handling: Animals should be handled with care. Washington, DC: The National Academies Press. APA has adopted separate guidelines for the use of nonhuman animals in research and teaching at the pre-college level. et al., 2008). From the earliest days of the organization, AWI has worked to foster better care and handling of animals in research facilities by encouraging laboratory personnel to provide the animals with comfortable housing with conspecifics; veterinary treatment including pain relief; and the opportunity to engage in species-typical behaviors—while sparing them needless suffering. 89–544) was signed into law by President Lyndon B. Johnson on August 24, 1966. for handling animals dosed with these hazardous materials. Ethical principles of psychologists and code of conduct (2002, Amended June 1, 2010). (8th Edition). Division on Earth and Life Studies. Laboratory animals or animals: Any vertebrate animal (e.g., traditional laboratory animals, agricultural animals, wildlife, and aquatic species) produced for or used in research, testing, or teaching. National Institutes of Health Office of Laboratory Animal Welfare (2002). General anesthesia 5. Guidelines for the humane transportation of research animals. Laboratory Animals 2020, Vol. Handling is generally restricted to individual or group transfer from cage to cage during cage change or to transfer of animals from and to the experimental envi-ronment. III. Retrieved September 27, 2011. Retrieved September 27, 2011. Washington, DC: The National Academies Press. 18.1): Handling: Animals should be handled with care. The use of appropriate and skilled handling is essential to ensure that animals readily accept or actively seek human contact and procedures are carried out efficiently. Guidelines for the humane transportation of research animals. If the researcher can not care for the animals, then animal care personnel must take the radiation safety training and become radiation workers. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities--a resource of proven value, now updated and expanded. National Research Council (2011). Animal Handling Techniques 1. All procedures carried out on nonhuman animals are to be reviewed by an institutional animal care and use committee (IACUC) to ensure that the procedures are appropriate and humane. Handling and restraint Laboratory animals are inevitably subjected to human contact throughout their lives, during both husbandry and experiments. Violations of the Ethical Principles of Psychologists and Code of Conduct by an APA member should be reported to the APA Ethics Committee by phone at 202-336-5930, or in writing to the APA Ethics Office, 750 First St., NE, Washington, DC 20002-424. Animal use is defined as the proper care, use, and humane treatment of laboratory animals produced for or used in research, testing, or teaching. Data’s of Laboratory Animals: Table 18.1 shows important data’s on some of the animals. Animal Care Technicians are found in clinical and research settings and are responsible for caring for laboratory animals. Aseptic (methods that minimize risks of infection) techniques must be used on laboratory animals whenever possible. American Psychological Association. The facilities housing laboratory animals should meet or exceed current regulations and guidelines (USDA, 1990, 1991; NIH, 2002) and are required to be inspected twice a year (USDA, 1989, NIH, 2002). Nonhuman animals may be used for educational purposes only after review by an IACUC or committee appropriate to the institution. Methods and welfare considerations in behavioral research with animals: Report of a National Institutes of Health Workshop. Temperature and Humidity 9. Training Package List. Noise is unavoidable in an animal care facility, but should be minimized. APA members working outside the United States must also follow all applicable laws and regulations of the country in which they conduct research. Because of this requirement, usually the researcher's lab personnel take care of the animals (e.g., become animal handlers). In the U.S., under the provisions of the Animal Welfare Act and the Guide for the Care and Use of Laboratory Animals (the Guide), published by the National Academy of Sciences, any procedure can be performed on an animal if it can be successfully argued that it is scientifically justified. Information and permit applications can be obtained from the Fish and Wildlife Service website. Chapter 6 - Training in Care, Handling, and Use of Laboratory Animals . Handling 10. Bethesda, MD: NIH. Field research, if strictly observational, may not require animal care committee approval (USDA, 2000). Roundtable on Science and Welfare in Laboratory Animal Use This roundtable brings together representatives from government, industry, animal advocacy groups, professional societies, and academic institutions to discuss science- and welfare-related issues dealing with the use of animals … U. S. Department of Agriculture (1991) Animal welfare; Standards; Part 3, Final Rule. All surgical procedures and anesthetization should be conducted under the direct supervision of a person who is trained and competent in the use of the procedures. The key to prevention of these types of injuries is proper training of research personnel by the animal care staff or other qualified individuals. While this is widely accepted for both the Learn about our remote access options. Ministry of Health, Labor and Welfare dated June 1, 2006 ). In general, psychologists should act on the assumption that procedures that are likely to produce pain in humans may also do so in other animals, unless there is species-specific evidence of pain or stress to the contrary. Working off-campus? Such uses must be compatible with the goals of the research, sound scientific practice, and the welfare of the animal. 1.2 Handling: how is it relevant and why is it important. Increase understanding of the species under study. Introduction. Disposition Authority Number . Public Health Service policy on the humane care and use of laboratory animals. American Veterinary Medical Association (2007) AVMA Guidelines on Euthanasia (PDF, 550KB). Washington, DC: US Government Printing Office. 18.12.5 Animal Handling. et al., 2004; Castelhano & Baumans, … Procedures in which the research animal is anesthetized and insensitive to pain throughout the procedure, and is euthanized (AVMA, 2007) before regaining consciousness are generally acceptable. LABORATORY ANIMAL HANDLING-CARE AND FACILITY . Phs policy on humane care and use of laboratory animals | olaw. THE NATIONAL ACADEMIES PRESS 500 Fifth Street, NW Washington, DC 20001. §2131 et. Ventilation 8. Several sections of the guidelines have yet to be finalised, but the Councils are now issuing those relating to housing and care of laboratory animals. Handle animals gently but firmly. Use of endangered, threatened or imported nonhuman animals must only be conducted with full attention to required permits and ethical concerns. Thiel College Institutional Animal Care and Utilization Committee Handling and Restraint of Small Laboratory Animals These guidelines have been developed to introduce investigative staff to procedures recommended for handling and restraint of small laboratory animals. As behavior is not only the focus of study of many experiments but also a primary source of information about an animal’s health and well-being, psychologists and their assistants should be informed about the behavioral characteristics of their nonhuman animal subjects. Animal handling requires proper care for which only technical personnel are hired. U. S. Department of Agriculture (1989) Animal welfare; Final Rules. used by all persons responsible for laboratory animals and particularly by licensees and others now working under the authority of the Animals (Scientific Procedures) Act, 1986. 1st Year ANIMAL HANDLING TECHNIQUES 2. Important parts of such work are teaching and research on the behavior of nonhuman animals, which contribute to the understanding of basic principles underlying behavior and to advancing the welfare of both human and nonhuman animals. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities—a resource of proven value, now updated and expanded. Whenever possible behavioral procedures should be used that minimize discomfort to the nonhuman animal. In general, laboratory animals should not be subjected to successive survival surgical procedures, except as required by the nature of the research, the nature of the specific surgery, or for the well-being of the animal. National Research Council (2006). The IACUC is charged with warranting that the university “ensure that all scientists, research technicians, animal technicians, and other personnel involved in animal care, treatment, and use are qualified to perform their duties. Research should be undertaken with a clear scientific purpose. Federal Register, 54(168), (Aug 31, 1989), 36112-36163. Federation of European Laboratory Animal Science Associations (FELASA) guidelines and recommendations, EU Council Directive 86/609/EEC, EU Animals and Birds (Care and Use of Animals for Scientific Purposes) Rules 2004, Singapore Experimental procedures that require prolonged aversive conditions or produce tissue damage or metabolic disturbances require greater justification and surveillance by the psychologist and IACUC. Dess, N. K. & Foltin, R. W. (2004). The committee must have representation from within the institution and from the local community. Cleanliness 4. Nonhuman animals reared in the laboratory must not be released into the wild because, in most cases, they cannot survive or they may survive by disrupting the natural ecology. Allergens: Laboratory animal allergies and associated asthma are among the most common conditions affecting individuals who work with laboratory animals. Consideration should be given to the possibility of using non-animal alternatives. Animal care programs require technical and husbandry support. Although handling is not standardized across labs, consistent gentle handling allows for less challenging behavioral testing, better data collection, and overall improved animal welfare… Labelling of the cages 7. Guidelines for the care and use of mammals in neuroscience and behavioral research. Laboratory Animals and Animal Tissue Disposal The use of laboratory animals in research and instruction is regulated by federal law ... handling animals must take special care when working with animals. Nonhuman animals taken from the wild should be trapped in a humane manner and in accordance with applicable federal, state, and local regulations. Current Protocols in Immunology is a comprehensive source for protocols and overviews in the field of immunology including, in vivo and in vitro assays to study lymphocyte cells, the isolation and differentiation of stem and progenitor cells, flow cytometry and cell sorting, and animal models of infections disease. National Institutes of Health Office of Laboratory Animal Welfare (2002). Return of any wild-caught animal to the field also carries risks, both to the formerly captive animals and to the ecosystem. NIH Publications No. et al., 1978; Maurer . Animal Welfare Act 7 U.S.C. Typically, allergies to animals result from repeated exposure to an animal’s dander, urine, saliva, serum, or other body tissues. Observational and other noninvasive forms of behavioral studies that involve no aversive stimulation to, or elicit no sign of distress from the nonhuman animal are acceptable. The conduct of all procedures is governed by Guideline I (Justification of Research) above. DAA-AU-2015-0032-0002 . Public Health Service policy on the humane care and use of laboratory animals. As with other species, hectic and jerky move-ments should be avoided. Animal Handling Techniques 1. Key components of the process are: 1. the inclusion of scientific committees to review research on priority welfare issues; 2. ownership of the individual Codes by the relevant stakeholders through their active participation in developing the Code; 3. measurable components to facilitate the development of assessment programs; and 4. a transparent process. Practical animal handling rodents and rabbit. Washington, DC: The National Academies Press. Psychologists should assume it their responsibility that all individuals who work with nonhuman animals under their supervision receive explicit instruction in experimental methods and in the care, maintenance, and handling of the species being studied. Laboratory Primate Newsletter Occupational Health and Safety in the Care and Use of Research Animals - National Research Council, 1997. Prevention of disease 3. Determine the replicability and generality of prior research. After this date users are encouraged to contact the APA Science Directorate to determine if this document remains in effect. Dead animals, animal tissue excreta, bedding, unused diet etc. The acquisition, care, housing, use, and disposition of nonhuman animals in research must be in compliance with applicable federal, state, and local, laws and regulations, institutional policies, and with international conventions to which the United States is a party. Multiple surgeries on the same animal must be justified and receive approval from the IACUC. 19. If routine handling procedures are aversive, animals are likely to develop anxiety U. S. Department of Agriculture (1990) Guinea pigs, hamsters, and rabbits; Final Rule. Care and Housing of Laboratory Animals, Advancing psychology to benefit society and improve lives. American Psychological Association. This section includes descriptions of each of 7 different components that collectively constitute a program of animal care … Take care to avoid blind spots and approach animals slowly so that they are always aware of your presence. Laboratory Animals: Regulations and Recommendations for the Care and Use of Animals in Research, Second Edition, is the only publication to offer a global compilation of standards on the care, welfare and use of animals in research.The book provides updated information that will be of great interest to professionals across laboratory animal science and biomedical research. Roundtable on Science and Welfare in Laboratory Animal Use This roundtable brings together representatives from government, industry, animal advocacy groups, professional societies, and academic institutions to discuss science- and welfare-related issues dealing with the use of animals in research. laboratory animal observation, record keeping and house keeping. Psychologists should make every effort to ensure that those responsible for transporting the nonhuman animals to the facility provide adequate food, water, ventilation, space, and impose no unnecessary stress on the animals (NRC, 2006). used by all persons responsible for laboratory animals and particularly by licensees and others now working under the authority of the Animals (Scientific Procedures) Act, 1986. Disposal of euthanized laboratory animals must be conducted in accord with all relevant legislation, consistent with health, environmental, and aesthetic concerns, and as approved by the IACUC. All over the world, animal models are used in pre-clinical research to learn more about how the body works, and to identify causes and develop treatments and cures for disorders and diseases. COVID-19 resources for psychologists, health-care workers and the public. Proper restraint and handling techniques are essential for reducing stress to laboratory animals, while at the same time allow animal care workers to perform their work with less chance of being scratched, bitten, kicked, etc. Data’s of Laboratory Animals: Table 18.1 shows important data’s on some of the animals. Contents: Contents Introduction Types of experimental animals used Animal handling Routes of drug administration in experimental animals Blood collection from experimental animals … As a field of study, psychology examines a broad range of research and applied areas. Assessing the Health and Welfare of Laboratory Animals: A Tutorial Site APA does not provide specific guidelines for the maintenance of psychological well-being of research animals, as procedures that are appropriate for a particular species may not be for others. 1st Year ANIMAL HANDLING TECHNIQUES 2. A program of animal care and use includes multiple components that work synergistically to support activities involving laboratory animals. Institutions should employ people who are trained (pharmacologist, veterinary scientists) for handling laboratory animals and should provide both formal as well as some on-duty training to ensure the proper handling of animals for which certain refresher training as well as induction programmes are run by certain animal welfare committees in different institutes and universities. MEENAKSHI M.Sc. Lab Animal. Psychologists should ensure that personnel involved in their research with nonhuman animals be familiar with these guidelines. Retrieved September 27, 2011. National Research Council (2003). The detection of signs of disease in animals 4. As a scientific and professional organization, APA recognizes the complexities of defining psychological well-being for both human and non-human animals. The Guide for the Care and Use of Laboratory Animals (Guide) will be used to develop training (PHS Policy IV.A.1.g). II. Psychologists who are familiar with the species, relevant literature, federal guidelines, and their institution's research facility context should consider the appropriateness of measures such as enrichment to maintain or improve psychological well-being of those species. AWI provides funding to laboratory personnel to conduct research focused on improving the housing and handling of animals in research, and has been at the forefront of efforts to provide nonhuman primates with social housing which addresses their behavioral needs to the greatest extent possible. Washington, DC: The National Academies Press. When euthanasia is appropriate, either as a requirement of the research or because it constitutes the most humane form of disposition of a nonhuman animal at the conclusion of the research: Euthanasia must be accomplished in a humane manner, appropriate for the species and age, and in such a way as to ensure immediate death, and in accordance with procedures outlined in the latest version of the “AVMA (American Veterinary Medical Association) Guidelines on Euthanasia (2007) (PDF, 550KB).". Postoperative monitoring and care, which may include the use of analgesics and antibiotics, should be provided to minimize discomfort, prevent infection and promote recovery from the procedure. 3. 02-5083. Proper animal handling and restraint is essential for proper ... Any questions regarding these resources should be directed to the Office of Animal Care and Use. View a copy of the APA Guidelines for the Use of Animals in Behavioral Projects in Schools (K – 12), or request a copy via email, by phone at (202) 336-6000, or in writing to the APA Science Directorate, Office of Research Ethics, 750 First St., NE, Washington, DC 20002-4242. Any deviations from these SOPs must be authorized and recorded by the Study Director. National Institutes of Health Office of Laboratory Animal Welfare (2002). Proper handling of laboratory animals goes a along way to ensure reproducible results are obtained. They are informed by Section 8.09 of the Ethical Principles of Psychologists and Code of Conduct (APA, 2010). Laboratory Animal Practitioner, Sep-14 "This is the only publication to offer a compilation of standards across the world in the care, welfare and use of animals in research, testing, and education. should be collected with care an in leak proof metal or plastic containers and incinerated. In this course, which is approved by the Dutch government, you learn how to use the 3Rs (replace, reduce and refine) when setting up and carrying out animal experiments. Institutions should employ people trained in laboratory animal science or provide for both formal and on the job training to ensure effective implementation of the programm. 54(3) 225–238! Laboratory Animals: Regulations and Recommendations for the Care and Use of Animals in Research, Second Edition, is the only publication to offer a global compilation of standards on the care, welfare and use of animals in research.The book provides updated information that will be of great interest to professionals across laboratory animal science and biomedical research. Laboratory animal medical records are the records of animal treatment and care, food given, medical condition, treatments, and observed mental and physical Basic mouse care and maintenance | protocol. Rahul Maheshwari, ... Rakesh K. Tekade, in Dosage Form Design Parameters, 2018. Essential responsibilities seen on an Animal Care Technician resume sample are cleaning cages, feeding animals, providing drinking water, administering medicine, maintaining required environment conditions, and collecting data. Taking an animal’s temperature 2. Posted on 6/24/2019. Please check your email for instructions on resetting your password. Consideration for the humane treatment and well-being of the laboratory animal should be incorporated into the design and conduct of all procedures involving such animals, while keeping in mind the primary goal of undertaking the specific procedures of the research project—the acquisition of sound, replicable data. Retrieved September 19, 2011. National Research Council (2008). Standard Operating Procedures for equipment use, maintenance, and calibration; for laboratory tests and methods; animal use issues such as identification, care, transfer, and necropsy; histopathology; handling test and control articles; data handling and storage. In C. K. Akins, S. Panicker, & C. L. Cunningham (Eds.). Contd. It is the Policy of the Public Health Service (PHS) to require institutions to establish and maintain proper measures to ensure the appropriate care and use of all animals involved in research, research training, and biological testing activities (hereinafter referred to as "activities") … Additional training is provided on an on-going basis as necessary to address revisions to PHS and/or USDA policy, animal care issues or other change in best practice. If you do not receive an email within 10 minutes, your email address may not be registered, Psychologists are encouraged to include instruction and discussion of the ethics and values of nonhuman animal research in all relevant courses. Federal Register, 55(32), (Feb 15, 1991), 6426-6505. While psychologists must conduct their teaching and research in a manner consonant with relevant laws and regulations, ethical concerns further mandate that psychologists consider the costs and benefits of procedures involving animals before proceeding with these activities. Public Health Service policy on the humane care and use of laboratory animals. While global research goals may be similar, there are significant differences between … Recognition and alleviation of pain in laboratory animals. These include: 1. Guide for the care and use of laboratory animals. Laboratory animal allergies are associated with the inhalation of allergens, such as animal dander and urinary proteins, into the lungs. It is the main federal law in the United States that regulates the treatment of animals in research and exhibition. Washington, DC: The National Academies Press. Federal Register, 55(136), (July 16, 1990), 28879-28884. Use of muscle relaxants or paralytics alone during surgery, without anesthesia, is unacceptable. Members on the committee were Gary Dunbar, PhD, Jennifer Higa, PhD, Theresa Jones, PhD, Barbara Kaminski, PhD, Scott Robinson, PhD, Rodney Swain, PhD, Pamela Scott-Johnson, PhD, Eric Wiertelak, PhD, and Sangeeta Panicker, PhD (Staff Liaison). Animals can be restrained either manually or … Retrieved April 8, 2010. Psychologists conducting field research should disturb their populations as little as possible, while acting consistent with the goals of the research. guide for the care and use of laboratory animal by the national academy of sciences courtesy of the national academies press, washington, d.c., usa national research council, usa public heath service policy on humane care and use of laboratory animals and arena/olaw institutional animal care and use committee guidebook Laboratory Animal Science Professional (LAS Pro) Laboratory Animals - The International Journal of Laboratory Animal Science and Welfare. Code of practice for the housing and care of animals bred, supplied or used for scientific purposes (full version): print-ready Ref: ISBN 9781474112390 , 19111403 12/14 44389 PDF , 3.42MB , 227 pages Retrieved April 8, 2010. Adopted by the APA Council of Representatives on February 24, 2012. OBJECTIVES To provide basic concept of animal handling to new user. 11. The handling of laboratory animals is specified in “Standards Relating to the Care and Management of Laboratory Animals and Relief of Pain” (Notice No.88 of the Ministry of Environment dated April 28, 2006). (pp 31-39). Although there are significant species differences when handling and restraining a laboratory animal, there are several important concepts that apply equally to all species. 6Department of Pharmacology 7. 1. Trypan Blue Exclusion Test of Cell Viability, Dextran Sulfate Sodium (DSS)‐Induced Colitis in Mice, The Isolation and Characterization of Murine Macrophages. Procedures involving more than momentary or slight aversive stimulation, which is not relieved by medication or other acceptable methods, should be undertaken only when the objectives of the research cannot be achieved by other methods. Animal facilities and programs should be operated in accord with this Guide, the Animal Welfare Regulations, or AWRs (CFR 1985); the Public Health Service Policy on Humane Care and Use of Laboratory Animals, or PHS Policy (PHS 1996); and other applicable federal (Appendixes C and D) state, and local laws, regulations, and policies. Assist the faculty in their mission of quality research with respect to the use of laboratory animals. (2010). Insect pests 4. Washington, DC: The National Academies Press. Such research on endangered species should not be conducted unless IACUC approval has been obtained and all requisite permits are obtained (see IV.D of this brochure.). 1. In animal experiments the well-being of laboratory animals is most important. 12. of productive restr ing. Provide results that benefit the health or welfare of humans or other animals. The rabbit is picked up from cage with the ears by one hand in a firm grip and another hand is placed under the hind-quarters to … 4. No animal shall be discarded until its death is verified. Other laws, policies, and guidelines may include additional species coverage or specifications for animal care and use, … To ensure their humane treatment and well-being, laboratory animals generally may not be released from institutional facilities. Laboratory Animal Handling . Laboratory animals are to be provided with humane care and healthful conditions during their stay in any facilities of the institution. Procedures involving the use of paralytic agents without reduction in pain sensation require particular prudence and humane concern. International Standards for the Care and Use of Laboratory Animals . Laboratory animals are inevitably subjected to human contact throughout their lives, during both husbandry and experiments. Enter your email address below and we will send you your username, If the address matches an existing account you will receive an email with instructions to retrieve your username, By continuing to browse this site, you agree to its use of cookies as described in our, Current Protocols Essential Laboratory Techniques, Current Protocols in Food Analytical Chemistry, Current Protocols in Magnetic Resonance Imaging, Current Protocols in Nucleic Acid Chemistry. Common Laboratory Animals and Handling Techniques Anuja.M.K. National Research Council (2006). To comply with the Animal Welfare Ordinance and avoid mishandling of animals in research. Laboratory animals in research and teaching: Ethics, care, and methods. and applicable federal regulations, policies, and guidelines, regarding personnel, supervision, record keeping, and veterinary care. Smaller laboratory animal require one to three changes per week, depending on population of the laboratory animals. In event that it is not possible to constitute an appropriate IACUC in the psychologist's own institution, psychologists should seek advice and obtain review from a corresponding committee of a cooperative institution. -- Research on nonhuman animals may not be conducted until the protocol has been reviewed by an appropriate animal care committee; typically, an Institutional Animal Care and Use Committee (IACUC), to ensure that the procedures are appropriate and humane. Environment, housing, and management guide for the care and. (Eds.). Wear disposable gloves. Guidelines for the humane transportation of research animals. The psychologist(s) should monitor the research and the subjects’ welfare throughout the course of an investigation to ensure continued justification for the research. And methods placed in three major categories rabbits ; Final Rule and resources... 6 - training in care, handling, procedural work and interventional behaviour assessments and Welfare of or. 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